Opteron 6378 's Advantages
Higher base frequency (2.4GHz vs 1.8GHz)
Lower TDP (115W vs 125W)
Intel Xeon Bronze 3408U 's Advantages
Released 10 years and 2 months late
Higher specification of memory (4000 vs 1866)
Newer PCIe version (5 vs 2)
Larger L3 cache size (22.5MB vs 8MB)
More modern manufacturing process (10nm vs 32nm)