Opteron 6378 's Advantages
Higher specification of memory (1866 vs 3)
Lower TDP (115W vs 130W)
Intel Xeon E5 2643 v2 's Advantages
Released 10 months late
Newer PCIe version (3 vs 2)
Higher base frequency (3.5GHz vs 2.4GHz)
Larger L3 cache size (15MB vs 8MB)
More modern manufacturing process (22nm vs 32nm)