Opteron 6378 's Advantages
Released 5 years and 9 months late
Higher specification of memory (1866 vs 2)
Newer PCIe version (2 vs 1)
More modern manufacturing process (32nm vs 90nm)
Opteron 2218 HE 's Advantages
Higher base frequency (2.6GHz vs 2.4GHz)
Lower TDP (68W vs 115W)