Opteron 6378 's Advantages
Lower TDP (115W vs 250W)
Xeon 6740E 's Advantages
Released 11 years and 7 months late
Higher specification of memory (6400 vs 1866)
Newer PCIe version (5 vs 2)
Larger L3 cache size (96MB vs 8MB)
More modern manufacturing process (5nm vs 32nm)