Opteron 6378 's Advantages
Lower TDP (115W vs 335W)
Xeon w7 3565X 's Advantages
Released 11 years and 9 months late
Higher specification of memory (4800 vs 1866)
Newer PCIe version (5 vs 2)
Higher base frequency (2.5GHz vs 2.4GHz)
Larger L3 cache size (82.5MB vs 8MB)
More modern manufacturing process (10nm vs 32nm)