Opteron 6386 SE 's Advantages
Lower TDP (140W vs 240W)
AMD EPYC 73F3 's Advantages
Released 8 years and 4 months late
Higher specification of memory (DDR4-3200 vs DDR3)
Newer PCIe version (4 vs 2)
Higher base frequency (3.5GHz vs 2.8GHz)
Larger L3 cache size (256MB vs 8MB)
More modern manufacturing process (7nm vs 32nm)