Opteron 6386 SE 's Advantages
Lower TDP (140W vs 320W)
AMD EPYC 9375F 's Advantages
Released 11 years and 11 months late
Higher specification of memory (6000 vs 1600)
Newer PCIe version (5 vs 2)
Higher base frequency (3.85GHz vs 2.8GHz)
Larger L3 cache size (256MB vs 8MB)
More modern manufacturing process (4nm vs 32nm)