Opteron 6386 SE 's Advantages
Higher base frequency (2.8GHz vs 2.7GHz)
Lower TDP (140W vs 205W)
Xeon Platinum 8280M 's Advantages
Released 6 years and 1 months late
Higher specification of memory (2933 vs 1600)
Newer PCIe version (3 vs 2)
Larger L3 cache size (38.5MB vs 8MB)
More modern manufacturing process (14nm vs 32nm)