Opteron 8216 HE (F3) 's Advantages
Lower TDP (68W vs 115W)
Opteron 1381 's Advantages
Released 2 years and 10 months late
Higher specification of memory (1333 vs 667)
Newer PCIe version (2 vs 1)
Higher base frequency (2.5GHz vs 2.4GHz)
More modern manufacturing process (45nm vs 90nm)