Opteron 8220 SE (F3) 's Advantages
Lower TDP (120W vs 360W)
AMD EPYC 9554P 's Advantages
Released 16 years and 3 months late
Higher specification of memory (4800 vs 667)
Newer PCIe version (5 vs 1)
Higher base frequency (3.1GHz vs 2.8GHz)
More modern manufacturing process (5nm vs 90nm)