Opteron 8220 's Advantages
Higher base frequency (2.8GHz vs 2.45GHz)
Lower TDP (95W vs 125W)
AMD EPYC 8124P 's Advantages
Released 16 years and 7 months late
Higher specification of memory (4800 vs 667)
Newer PCIe version (5 vs 1)
More modern manufacturing process (5nm vs 90nm)