Opteron 8220 's Advantages
Higher base frequency (2.8GHz vs 2.1GHz)
Lower TDP (95W vs 350W)
Intel Xeon Platinum 8468 's Advantages
Released 15 years and 11 months late
Higher specification of memory (DDR5-4800 vs DDR2-667)
Newer PCIe version (5 vs 1)