Opteron 8222 SE 's Advantages
Higher base frequency (3GHz vs 2.5GHz)
Lower TDP (120W vs 270W)
Intel Xeon W 3375 's Advantages
Released 14 years and 3 months late
Higher specification of memory (3200 vs 667)
Newer PCIe version (4 vs 1)
More modern manufacturing process (10nm vs 90nm)