Opteron 8222 's Advantages
Higher base frequency (3GHz vs 2.7GHz)
Lower TDP (95W vs 280W)
AMD Ryzen Threadripper PRO 5995WX 's Advantages
Released 14 years and 7 months late
Higher specification of memory (3200 vs 667)
Newer PCIe version (4 vs 1)
More modern manufacturing process (7nm vs 90nm)