Xeon 6740E 's Advantages
Released 11 years and 7 months late
Higher specification of memory (6400 vs 1866)
Newer PCIe version (5 vs 2)
Larger L3 cache size (96MB vs 8MB)
More modern manufacturing process (5nm vs 32nm)
Opteron 6378 's Advantages
Lower TDP (115W vs 250W)