Xeon 6780E 's Advantages
Released 12 years and 3 months late
Higher specification of memory (6400 vs 3)
Newer PCIe version (5 vs 3)
Larger L3 cache size (108MB vs 10MB)
More modern manufacturing process (5nm vs 32nm)
Intel Xeon E5 2643 's Advantages
Higher base frequency (3.3GHz vs 2.2GHz)
Lower TDP (130W vs 330W)