Xeon E 2488 's Advantages
Released 2 years and 9 months late
Higher specification of memory (4800 vs 3200)
Newer PCIe version (5 vs 4)
Higher base frequency (3.2GHz vs 2.75GHz)
Lower TDP (95W vs 225W)
AMD EPYC 7453 's Advantages
Larger L3 cache size (64MB vs 24MB)
More modern manufacturing process (7nm vs 10nm)