AMD Radeon Pro WX 8100 's Advantages
More VRAM (8GB vs 4GB)
Larger VRAM bandwidth (512.0GB/s vs 112.0GB/s)
2816 additional rendering cores
AMD Radeon Pro W6400 's Advantages
Released 4 years and 1 months late
Boost Clock has increased by 55% (2331MHz vs 1500MHz)
Lower TDP (50W vs 230W)