AMD Radeon R9 280 's Advantages
Larger VRAM bandwidth (240.0GB/s vs 224.0GB/s)
AMD Radeon Pro W6600 's Advantages
Released 7 years and 3 months late
Boost Clock has increased by 177% (2580MHz vs 933MHz)
More VRAM (8GB vs 3GB)
Lower TDP (100W vs 200W)