AMD EPYC 7261 's Advantages
Released 8 years and 3 months late
Higher specification of memory (2666 vs 3)
Newer PCIe version (3 vs 2)
Higher base frequency (2.5GHz vs 2.4GHz)
Larger L3 cache size (32MB vs 12MB)
More modern manufacturing process (14nm vs 32nm)
Intel Xeon E5645 's Advantages
Lower TDP (80W vs 170W)