AMD EPYC 7281 's Advantages
Released 8 years and 3 months late
Higher specification of memory (2666 vs 1066)
Newer PCIe version (3 vs 2)
Larger L3 cache size (32MB vs 8MB)
More modern manufacturing process (14nm vs 45nm)
Xeon E5540 's Advantages
Higher base frequency (2.533GHz vs 2.1GHz)
Lower TDP (80W vs 170W)