AMD EPYC 7443 's Advantages
Released 8 years and 4 months late
Higher specification of memory (3200 vs 1866)
Newer PCIe version (4 vs 2)
Higher base frequency (2.85GHz vs 2.5GHz)
Larger L3 cache size (128MB vs 8MB)
More modern manufacturing process (7nm vs 32nm)
Opteron 6380 's Advantages
Lower TDP (115W vs 200W)