AMD EPYC 7453 's Advantages
Released 1 years and 11 months late
Higher specification of memory (3200 vs 2933)
Newer PCIe version (4 vs 3)
Higher base frequency (2.75GHz vs 2.1GHz)
More modern manufacturing process (7nm vs 14nm)
Lower TDP (225W vs 250W)
Intel Xeon Platinum 9221 's Advantages
Larger L3 cache size (71.5MB vs 64MB)