AMD EPYC 7453 's Advantages
Released 13 years and 6 months late
Higher specification of memory (3200 vs 667)
Higher base frequency (2.75GHz vs 1.8GHz)
Larger L3 cache size (64MB vs 2MB)
More modern manufacturing process (7nm vs 65nm)
Opteron 8346 HE 's Advantages
Lower TDP (68W vs 225W)