AMD EPYC 7642 's Advantages
Released 7 years and 3 months late
Higher specification of memory (3200 vs 3)
Newer PCIe version (4 vs 2)
Larger L3 cache size (256MB vs 8MB)
More modern manufacturing process (7nm vs 32nm)
Opteron 6278 's Advantages
Lower TDP (115W vs 225W)