AMD EPYC 7643 's Advantages
Released 12 years and 10 months late
Higher specification of memory (3200 vs 667)
Higher base frequency (2.3GHz vs 1.8GHz)
Larger L3 cache size (256MB vs 2MB)
More modern manufacturing process (7nm vs 65nm)
Opteron 8346 HE (B3) 's Advantages
Lower TDP (68W vs 225W)