Intel Xeon E 2378 's Advantages
Released 9 years and 6 months late
Higher specification of memory (3200 vs 3)
Newer PCIe version (4 vs 3)
More modern manufacturing process (14nm vs 32nm)
Lower TDP (65W vs 130W)
Intel Xeon E5 2680 's Advantages
Higher base frequency (2.7GHz vs 2.6GHz)
Larger L3 cache size (20MB vs 16MB)