Intel Xeon E 2378 's Advantages
Higher base frequency (2.6GHz vs 1.9GHz)
Lower TDP (65W vs 350W)
Intel Xeon w9 3495X 's Advantages
Released 1 years and 5 months late
Higher specification of memory (4800 vs 3200)
Newer PCIe version (5 vs 4)
Larger L3 cache size (105MB vs 16MB)
More modern manufacturing process (10nm vs 14nm)