Intel Xeon E 2378 's Advantages
Higher base frequency (2.6GHz vs 2GHz)
Lower TDP (65W vs 250W)
Xeon 6746E 's Advantages
Released 2 years and 9 months late
Higher specification of memory (5600 vs 3200)
Newer PCIe version (5 vs 4)
Larger L3 cache size (96MB vs 16MB)
More modern manufacturing process (5nm vs 14nm)