Intel Xeon E3 1220 's Advantages
Higher base frequency (3.1GHz vs 2.3GHz)
Lower TDP (80W vs 320W)
AMD EPYC 9645 's Advantages
Released 13 years and 6 months late
Higher specification of memory (6000 vs 3)
Newer PCIe version (5 vs 3)
Larger L3 cache size (256MB vs 8MB)
More modern manufacturing process (3nm vs 32nm)