Intel Xeon E3 1280 's Advantages
Higher base frequency (3.5GHz vs 2.5GHz)
Lower TDP (95W vs 170W)
AMD EPYC 7261 's Advantages
Released 7 years and 2 months late
Higher specification of memory (2666 vs 3)
Larger L3 cache size (32MB vs 8MB)
More modern manufacturing process (14nm vs 32nm)