Intel Xeon E3 1280 's Advantages
Higher base frequency (3.5GHz vs 2.4GHz)
Lower TDP (95W vs 225W)
Intel Xeon Platinum 8351N 's Advantages
Released 10 years late
Higher specification of memory (2933 vs 3)
Newer PCIe version (4 vs 3)
Larger L3 cache size (54MB vs 8MB)
More modern manufacturing process (10nm vs 32nm)