Intel Xeon E5 2450 's Advantages
Higher base frequency (2.1GHz vs 1.9GHz)
Lower TDP (95W vs 350W)
Intel Xeon w9 3495X 's Advantages
Released 10 years and 9 months late
Higher specification of memory (4800 vs 3)
Larger L3 cache size (105MB vs 20MB)
More modern manufacturing process (10nm vs 32nm)