Intel Xeon E5 2643 v2 's Advantages
Higher base frequency (3.5GHz vs 2.75GHz)
Lower TDP (130W vs 225W)
AMD EPYC 7453 's Advantages
Released 7 years and 6 months late
Higher specification of memory (3200 vs 3)
Newer PCIe version (4 vs 3)
Larger L3 cache size (64MB vs 15MB)
More modern manufacturing process (7nm vs 22nm)