Intel Xeon E5 2643 's Advantages
Higher base frequency (3.3GHz vs 2.5GHz)
Lower TDP (130W vs 200W)
AMD EPYC 9224 's Advantages
Released 10 years and 8 months late
Higher specification of memory (4800 vs 3)
Newer PCIe version (5 vs 3)
Larger L3 cache size (64MB vs 10MB)
More modern manufacturing process (5nm vs 32nm)