Intel Xeon E5 2643 's Advantages
Higher base frequency (3.3GHz vs 2.9GHz)
Lower TDP (130W vs 135W)
Intel Xeon E5 2666 v3 's Advantages
Released 2 years and 8 months late
Higher specification of memory (2133 vs 3)
Larger L3 cache size (25MB vs 10MB)
More modern manufacturing process (22nm vs 32nm)