Intel Xeon E5 2643 's Advantages
Lower TDP (130W vs 250W)
Intel Xeon W 3335 's Advantages
Released 9 years and 4 months late
Higher specification of memory (3200 vs 3)
Newer PCIe version (4 vs 3)
Higher base frequency (3.4GHz vs 3.3GHz)
Larger L3 cache size (24MB vs 10MB)
More modern manufacturing process (10nm vs 32nm)