Intel Xeon E5 2680 's Advantages
Lower TDP (130W vs 200W)
AMD EPYC 7443 's Advantages
Released 9 years late
Higher specification of memory (3200 vs 3)
Newer PCIe version (4 vs 3)
Higher base frequency (2.85GHz vs 2.7GHz)
Larger L3 cache size (128MB vs 20MB)
More modern manufacturing process (7nm vs 32nm)