Intel Xeon E5 2680 's Advantages
Higher base frequency (2.7GHz vs 2.45GHz)
Lower TDP (130W vs 280W)
AMD EPYC 7763 's Advantages
Released 9 years late
Higher specification of memory (3200 vs 3)
Newer PCIe version (4 vs 3)
Larger L3 cache size (256MB vs 20MB)
More modern manufacturing process (7nm vs 32nm)