Intel Xeon E5 2680 's Advantages
Higher base frequency (2.7GHz vs 2GHz)
Lower TDP (130W vs 150W)
Intel Xeon Gold 5416S 's Advantages
Released 10 years and 10 months late
Higher specification of memory (4400 vs 3)
Newer PCIe version (5 vs 3)
Larger L3 cache size (30MB vs 20MB)
More modern manufacturing process (10nm vs 32nm)