Intel Xeon E5640 's Advantages
Higher base frequency (2.666GHz vs 2.5GHz)
Lower TDP (80W vs 270W)
Intel Xeon W 3375 's Advantages
Released 11 years and 4 months late
Higher specification of memory (3200 vs 3)
Newer PCIe version (4 vs 2)
Larger L3 cache size (57MB vs 12MB)
More modern manufacturing process (10nm vs 32nm)