Intel Xeon E5649 's Advantages
Larger L3 cache size (12MB vs 8MB)
Lower TDP (80W vs 82W)
Intel Xeon E3 1280 v3 's Advantages
Released 2 years and 4 months late
Higher specification of memory (4 vs 3)
Newer PCIe version (3 vs 2)
Higher base frequency (3.6GHz vs 2.533GHz)
More modern manufacturing process (22nm vs 32nm)