Intel Xeon Platinum 8380 's Advantages
Released 8 years and 5 months late
Higher specification of memory (DDR4-3200 vs DDR3)
Newer PCIe version (4 vs 2)
Larger L3 cache size (60MB vs 8MB)
Opteron 6378 's Advantages
Higher base frequency (2.4GHz vs 2.3GHz)
Lower TDP (115W vs 270W)