Opteron 1381 's Advantages
Higher base frequency (2.5GHz vs 1.9GHz)
Lower TDP (115W vs 250W)
Xeon 6766E 's Advantages
Released 15 years late
Higher specification of memory (6400 vs 1333)
Newer PCIe version (5 vs 2)
Larger L3 cache size (108MB vs 6MB)
More modern manufacturing process (5nm vs 45nm)