Opteron 2212 HE (F3) 's Advantages
Lower TDP (68W vs 155W)
AMD EPYC 7452 's Advantages
Released 13 years late
Higher specification of memory (3200 vs 2)
Newer PCIe version (4 vs 1)
Higher base frequency (2.2GHz vs 2GHz)
More modern manufacturing process (7nm vs 90nm)