Opteron 2212 HE (F3) 's Advantages
Lower TDP (68W vs 320W)
AMD EPYC 9645 's Advantages
Released 18 years and 2 months late
Higher specification of memory (6000 vs 2)
Newer PCIe version (5 vs 1)
Higher base frequency (2.3GHz vs 2GHz)
More modern manufacturing process (3nm vs 90nm)