Opteron 2216 HE (F3) 's Advantages
Lower TDP (68W vs 400W)
AMD EPYC 9684X 's Advantages
Released 16 years and 10 months late
Higher specification of memory (4800 vs 2)
Newer PCIe version (5 vs 1)
Higher base frequency (2.55GHz vs 2.4GHz)
More modern manufacturing process (5nm vs 90nm)