Opteron 2216 HE (F3) 's Advantages
Higher base frequency (2.4GHz vs 2.15GHz)
Lower TDP (68W vs 100W)
AMD EPYC Embedded 3451 's Advantages
Released 11 years and 6 months late
Higher specification of memory (2666 vs 2)
Newer PCIe version (3 vs 1)
More modern manufacturing process (14nm vs 90nm)