Opteron 2216 HE (F3) 's Advantages
Lower TDP (68W vs 130W)
Intel Xeon E5 4650 's Advantages
Released 5 years and 9 months late
Higher specification of memory (3 vs 2)
Newer PCIe version (3 vs 1)
Higher base frequency (2.7GHz vs 2.4GHz)
More modern manufacturing process (32nm vs 90nm)