Opteron 2220 SE (F3) 's Advantages
Lower TDP (119W vs 170W)
AMD EPYC 4564P 's Advantages
Released 17 years and 9 months late
Higher specification of memory (5200 vs 2)
Newer PCIe version (5 vs 1)
Higher base frequency (4.5GHz vs 2.8GHz)
More modern manufacturing process (5nm vs 90nm)